Thursday, June 27, 2019

Infertility in men: Symptoms and Causes


Studies say that 15% of couples are not fit for conceiving a child. They are not able to conceive even after attempting frequent sexual intercourse without any protection for years. One-third of these couples have the infertility issue in men.



The reason behind male infertility is low sperm count, blockages that abort the delivery of sperm or abnormal sperm function. There can be numerous other reasons behind male infertility like injuries, illness, chronic health issues and lifestyle choices.



Unable to produce sperm or conceive a child is no doubt stressful, but one can avail various male fertility treatments.


Symptoms of Potential male Infertility.

Symptoms which depend upon the causes of infertility. They can consist:

Problems with erections and ejaculation
Changes in sexual desire
Small, firm testicles
Changes in hair growth
Pain, lump, or swelling in the testicles


Causes of male infertility

Listed below are some of the major causes of Male Infertility:
     When the sperm’s passage get obstructed
     Hormone-related issues
     Low sperm count
     Impotence or other functional problem.

Obstructions causing infertility in men

Sperm is manufactured inside testicles, thereafter it passes through epididymis (a series of small tubes) spending about 2-10 days. In this span, the sperm gets matured and come into vas deferens (a larger tube). The vas deferens channel the sperm into the ejaculatory duct, where it comes in contact with seminal fluid which comes from the prostate gland and the seminal vesicles to form a mixture.

The semen is forced into the urethra and finally out of the penis due to muscular contractions during ejaculation. Around one in three cases of infertility in men is due to absences or blockage of tubes (the vas deferens as well). Injury or vasectomy can be a reason behind the blockage or absence of tubes.

Problems with sperm causing infertility in men

Genetic factors are thought to be responsible for the problems with sperm count or its quality. The sperm problems can also lead to the absence of tiny fragments of the male chromosome in some men. This may result in:

     Azoospermia (Absent sperm) - when the sperm is absent in semen. Testicular failure or blocked tubes can lead to this condition.

     Oligospermia (Low sperm count) – the sperm in the ejaculate is not in a sufficient amount to bring about conception.

     Abnormal shape – healthy sperm looks like a streamlined tadpole in shape. Sperm with abnormal shape may face problems while penetrating the egg’s surface.

     Poor motility – a healthy sperm swims through the woman's reproductive system with the help of its lashing tail. Sperm having poor motility may swim clumsily or sometimes not at all.

Infertility in men due to Functional problems.

Some of the Functional problems that can lead to male infertility include:

     Impotence – the inefficiency to maintain or get an erection needed for sexual intercourse

     Prostatectomy – when the prostate gland is removed surgically leading to side effects, as well as impotence, infertility and incontinence.

     Ejaculation issues – retrograde (when semen doesn’t emerge through the penis and enters the bladder) as well as immature ejaculation.

     Problems related to the testicles due to some infection, injury or chemotherapy

     Antibodies – the sperm activity is hindered by the antibodies made by man’s immune system, like lowering the sperm’s capacity to latch onto an egg from his partner.

     Certain disorders – diabetes, multiple sclerosis as well as other syndromes can lead to problems in erection and ejaculation.

Hormonal problems causing infertility in men

A series of glands and hormones they release are responsible for regulating the levels of male sex hormones. Hormone production in the testicles guided by the hypothalamus is influenced by the pituitary gland in the brain The failure to manufacture a good amount of the hormone gonadotrophin is relatively an uncommon reason for male infertility.

Apart from the mentioned above factors, there are many other medical, environmental, health, lifestyle and other causes which lead to infertility in men.


Mohak laparoscopy and infertility center is one of the Best IVF center in Indore, India. which provides infertility treatment at an affordable cost in indore with the Highest Success Rate. If you're planning to schedule an appointment for infertility treatment to the leading IVF center, Mohak laparoscopy and infertility center is an ideal place for infertile couples. Call us : 7898047572. 

For More Post : WHAT IS PCOS/PCOD?

Wednesday, June 19, 2019

WHAT IS PCOS/PCOD?

PCOS/PCOD stands for Polycystic Ovarian Syndrome/Disease that is characterised by irregular or prolonged Menstrual periods in women of reproductive age.

PCOS is caused due to Hormonal Imbalance in female bodies and is a leading cause of Infertility in females.

PCOS is found in around 5-7% of women of reproductive age.

WHAT MAKES PCOS A POTENTIAL RISK FACTOR?


PCOS often goes undiagnosed because of the lack of awareness among young females and, is mostly ignored by working women.

PCOS brings in a variety of changes in the female body such as -

• Irregularity of menses (periods) is the most common manifestation of PCOS and is also the prime symptom of PCOS. It may also lead to discoloration of period blood.

• Hperinsulinemia (Excess of insulin hormone) and insulin resistance leads to a gain in body weight turning majority of women with PCOS into Obese women. Excess of these hormones in the body often leads to early onset of Type 2 Diabetes Mellitus (DM) disorder.
• 
Hyperandrogenism (Excess male hormones) that leads to excessive body hair, facial hair, acne and other problems.
• Episodes of severe abdominal pain arise due to formation of cysts on the ovarian wall which is often considered to be cramps and is ignored by women.

• Dyslipidemia (Irregular fat depositions) is a common manifestation of insulin resistance in females with PCOS with higher levels of blood cholesterol.

• Insulin resistance may even lead to Hyperpigmentation and diffuse velvety thickening of skin especially around arm-pits, groins and neck (Acanthosis Nigricans).

• Cardiovascular Diseases often occur due to improper lipid metabolism in the body.

All these factors lead to infertility and also physical and mental ill-being of the patient.

WHEN TO CONTACT YOUR DOCTOR?

PCOS is generally diagnosed in married women when they are unable to conceive children, however through general awareness and monitoring, PCOS can be diagnosed at an earlier stage and is resolved by regular treatment.
Some eminent signs are:

• When you miss your periods continuously for two cycles.
• There is scanty amount of blood in your period or if it shows discoloration.
• Excessive hair loss/male pattern baldness.
• Excessive acne.

TREATMENT OF PCOS:

The treatment of PCOS is based on management of exclusive signs and symptoms in the patient such as- Infertility, Obesity, Acne and/or Hirsutism (excessive body hair) etc.

Specific treatment revolves around management of lifestyle and if required Medication.


Mohak IVF- test tube baby center is one of the Best infertility hospital in indore provides infertility treatment with high international standards and assisted reproductive technologies like IUI, IVF/ ICSI treatment, IMSI etc. Mohak IVF provides high success ratio IVF treatment at affordable ivf cost in indore. Highly experienced and fully professionals ivf specialist/doctor in indore give their full efforts to make your parenthood dreams comes true.

More Post How is Female Infertility treated using IVF?

Tuesday, June 11, 2019

How is Female Infertility treated using IVF?


Female Infertility :

It has been observed in a study that about 10-15% of couples face problems with conception. There is a range of causes which affect fertility in women as well as men. Those couples who might be getting no result even after making attempts to have a baby may be keen on seeking IVF treatments. Located in the heart of India – Indore and established in the year of 2010, Mohak IVF is known for its excellence for making unfertile women successfully produce babies.

What is IVF technology?

Usually known by its short name IVF, In Vitro Fertilization is a new age assisted reproductive technology. This technology involves the extraction of eggs and retrieving a sperm sample, thereafter integration of an and sperm is done manually in a laboratory dish. The formed embryo(s) is then moved into the uterus.

How is Female Infertility treated using IVF?

IVF treatment procedure provides treatments for couples who can not have a biological child for more than a year (12 months). It helps anyone who has already gone through several options of effectless fertility treatment, or maybe in the case of the Fallopian tube congestion or may be low sperm quality, like initial treatment - both can be treated only by IVF.

Infertility is a problem for women who are unable to conceive after 12 months of pregnancy. It is quite common, about 15% of the pairs are facing problems in conceiving even after making attempts. Fertility problems can occur both in men as well as women and in some cases.


In Vitro Fertilization or in vitro fertilization, the option is in a comprehensive clinical process in which the eggs and sperm are obtained and then fertilized manually in the laboratory and then restored in the uterus. For the pairs who failed to conceive naturally, of course, the ultimate goal of the IVF process is the result of a healthy full pregnancy.

What Causes Female Infertility?

A woman may be infertile because of a number of reasons:

Cervical issues. Due to certain conditions that prevent sperm from going through the cervical canal.

Damage to your fallopian tubes. These structures take eggs from your ovaries, which produce eggs, in a uterus where the child develops. In the case of scars after pelvic inflammation, endometriosis and pelvic surgery, they may be damaged. Which can stop sperm from reaching the egg?

Uterine trouble. You may have polyps and fibroids that interfere with pregnancy. Inflammation of the uterus and fibroids occurs when multiple cells grow in the endometrium, reaching the uterus. Other uterine deficiencies can be disturbances.

Hormonal problems. You can not be pregnant because your body does not pass through normal hormonal changes, which leads to the release of an egg from the ovary and to the thickening of the endometrium.

"Unexplained" infertility. This is something which affects about 20% of couples where the exact reasons behind pregnancy are never seen.

Female Infertility Treatments

Most women in their mid-30s or onwards wanting to have a baby might experience issues since their eggs start to fall as they are of lower quality. Ecological elements such as smoking cigarettes, excess weight, sexual background and also alcoholic beverages are usually very high-risk elements that have an effect on Female Infertility Treatments.
Unexplained infertility is an event that accounts for 15% of all non-regular participants which can be seen in all the important researches, without diagnosing the doctor due to the lack of experience of the children.


Get the solutions related to infertility with one of the best fertility doctor intend to provide the best infertility treatment in indore. She is one of the leading Infertility specialists in Indore.

More Post: What is the IVF Treatment Cost in India?

Wednesday, June 5, 2019

What is the IVF Treatment Cost in India?

Age is an important factor:

With the increase in age, a woman’s ability to conceive a baby starts to decline. An important point to note is that when you use your own eggs, your rate of success is inversely proportional to your age. The younger you are more is the chances of success.

What Infertility Disorders Can Be Treated In India?

With the advancement in medical technology, we can see a lot of IVF centres across India which are capable of treating all types of Infertility disorders and help childless women gain a chance to conceive. Here are some of the disorders which are treated:

     Blocked or damaged Fallopian tubes.
     Ovulation-related disorders.
     Sperm-related disorders like low sperm count.
     Endometriosis.

Patients who are not willing a huge amount on treatment can sight India for world-class infertility treatment. The doctors are reputed and known for their personal attention to each patient. Apart from this, they are even known for migrating miles in order to make sure that the treatments they provided are successful.

How much does IVF treatment cost in India?

This is something every patient think before making up their mind for an IVF cycle and selecting an IVF centre. In this article, we have presented you with a basic structure of rates. The IVF Cost in India which includes all diagnostic and surgical procedures, test and treatments generally ranges between 1 to 1.25 Lakh per cycle. The cost of IVF cycles in India or across the world is gaining inclination because of modern diagnostic test, and treatment methods such as IUI, hysteroscopy, laparoscopy are taken in assistance to aid and facilitate infertility treatments cost. This is why, there is no upper limit to the amount of money one can spend in desire for a baby.


ART or Assisted Reproductive Technology is the bundle of all options of fertility treatment in which both sperm and eggs are managed. The ART process consists of surgical extraction of eggs from the ovaries of a woman. Thereafter, the extracted eggs are merged with the sperms. The next process is of restoration of these sperms and ovaries back to either a woman's body or someone who can keep it on behalf of the original mother.

IVF cost – In vitro preparation is among the ART techniques of letting impregnation of the man, gametes of woman (sperm and an egg) occur outside the woman’s body system..

As seen through a recent Canadian and US survey, 40 out of 100 international couples are choosing India or putting India on the top for their IVF treatment whereas 50 of the couples were found to be looking for IVF with donor eggs. This is a pride moment for us to see that in India the success rate of IVF every year is attaining a new height.

Disclaimer: Please note that rates are subject to change as per hospitals, spread across the nation.

IVF treatment cost in Indore:

Talking about the IVF cost in Indore, it can vary in between a certain range depending upon whether it is including or excluding the cost of prescribed medicines and injections. Mohak IVF is one of the most renowned IVF centres in Indore, so it is suggested to call and speak to the executive to clear all your cost-related queries. The cost of IVF cycle is even not a fixed cost as many people have been found to spend more than Rs. 600,000 for the test tube baby treatment. There are numerous factors which influence the cost of IVF treatments fluctuations. The reasons behind the variations of costs may be the patient’s medical history, fertility issues or the need for several other treatments along with IVF. Mohak IVF is known for providing the most affordable IVF cost in Indore.

In case an IVF clinic offers an IVF cycle treatment for less than Rs.1,50,000, it is to be noted there may be some additional or hidden extra costs which will be billed later. Before going any further, the patient should always clear all the doubts related to the cost of IVF treatment like the cost of ultrasound, fertility drugs, blood work and monitoring etc. Raising
well-researched questions prior to the treatment can help you save from getting shocked because of surprisingly high medical bills and disputes with the clinic.

IVF clinics across India and their specialists have the expertise in performing satisfactory solutions for infertility. A patient need not to worry about getting treatment and conceiving as there are numerous reputed IVF centres across India which increases the chances of conceiving. This helps them see their dream of becoming a happy parent come true! 


Mohak IVF is one of the best test tube baby center in indore is run by most popular and highly experienced IVF specialist and Fertility specialist. The centre have high success rate with focused on patient dedicated individual care. 



Sunday, June 2, 2019

FET might be susceptible to an imperfect environment


“Can FET and fresh ET outcome in IVF cycles be affected by the open environment air pollution?”

Introduction:

IVF outcomes and human infertility can be a result of air pollution around us. It’s indicated in Choe et al [1] study that lower pregnancy rates in IVF cycles can be associated with ambient air pollution while controlled ovarian stimulation as well as the post-transfer period.
Choe et al1 study indicated lower pregnancy rates in IVF cycles may be linked to ambient air pollution during controlled ovarian stimulation and the post-transfer period. Do the outcomes of frozen-thawed embryo transfer (FET) and fresh transfer are differentially affected by
open-air pollution?

Summary:


Between January 2013 and December 2016, Wang et al [2] studied the adverse effects of air pollution in 11148 patients contributing to 16290 transfer cycles for IVF treatment cycles.
The average age of the cohort was recorded to be 31.5 years. In order to estimate the daily ambient exposures to six main pollutants ( CO, O3, SO2, NO2, PM2.5, PM10) inverse distance weighing interpolation was used at an IVF clinical site, bestow to the data recorded at the
fixed air quality monitoring stations inside the city. The exposure for every cycle was shown as the daily mean concentration of contaminants (pollutants) from oocyte retrieval to embryo transfer/cryopreservation. Analysis of exposures was performed on every quarter basis. A general equating estimate was used to study the relationship between pollutants and IVF results. The rate of clinical pregnancy and the rate of live birth of the course were recorded to be 55.1% and 47.1% respectively. 4013 patients among the included cycles, got 5299 FET cycles, bringing about 42.7% live birth per ET, while 9553 patients got 10991 new transfer cycles, bringing about 49.2% to live birth per ET. Raised SO2 and O3 levels were
essentially related with lower rates of live birth in FET cycles, while none of the pollutants
was significantly linked with bringing down of IVF results in new transfer cycles. The FET cycles in the most elevated quartile of SO2 and O3 exposure had essentially lower rates of live birth (balanced OR) in correlation with those in the least quartile. Models including all transfer cycles and collaboration terms (FET exposures) recommended that FET altogether improved the impacts of SO2 and O3 exposures on IVF results (P < 0.001). Representing every six contaminations, women in the top quartile of SO2 still had the least rates of live birth (OR 0.61, 95%CI 0.47–0.80).

Conclusion:

According to this study, embryos may be more vulnerable to a suboptimal environment which are undergoing FET in comparison to those which are undergoing fresh transfer. Elevated SO2 and O3 levels at the location of IVF were found to be significantly linked with lower rates of live birth following FET whereas it did not show any adverse effect on the contemporary new transfer results. In the locations and seasons which are heavily polluted, due to dynamic changes of the ambient air pollutant (specifically gaseous), fluctuation in FET outcomes can be seen.

References:

1.  Xin Li Wang, Jiali Cai, Lanlan Liu, Xiaoming Jiang, Ping Li, Aiguo Sha, Jianzhi Ren; Association between outdoor air pollution during in vitro culture and the outcomes of frozen-thawed embryo transfer, Human Reproduction, Volume 34, Issue 3, 1 March 2019, Pages 441–451,
https://doi.org/10.1093/humrep/dey386
2.  Choe SA, Jun YB, Lee WS, Yoon TK, Kim SY. Association between ambient air pollution and pregnancy rate in women who underwent IVF. Hum Reprod. 2018 Jun
1;33(6):1071-1078. doi: 10.1093/humrep/dey076. PubMed PMID: 29659826


Mohak laparoscopy and infertility center is one of the best fertility centre in indore. We offer male & female infertility treatment, ICSI and assisted reproduction at affordable ivf cost in indore.