Failure of IVF is very disheartening, but it is not the end. Still you have the hope to get successful IVF. We know a lot of people who struggle to conceive and opt for In Vitro Fertilization (IVF) treatment. With proper guidance of your IVF specialist, most couples get the gift of parenthood, it is a joyful experience and the hurdles doesn’t matter when the couple achieve it.
Here we will discuss the different causes of IVF failures and how to approach for the next step. But the process IVF is not the only thing that matters, we have encountered with a lot of couples who have faced repeated IVF failures.
Common Causes Of Repeated IVF Failures
- Poor Endometrium status: – Thin endometrium lining is not suitable for embryo implantation.
- Uterine Abnormality: – Uterine fibroid/cysts/endometrial polyps/septum and so on, can be the cause of implantation failures.
- Embryo Quality: – Poor quality of embryo or chromosomal abnormality in embryo causes difficulty in implantation, or in case if they gets implanted, they may not remain for a long time.
When embryonic layer surrounding the oocyte, known as the zona is thicker than usual then it can also leads to implantation failure. It happens because of the failure of sperms ability to break the zona during fertilization.
- Genetic Abnormality :– Any minor defect like chromosomal microdeletions, can compromise the quality of gametes and hence embryo.
- Maternal health: – Uncontrolled diabetes, thyroid disorders, etc., can be the conditions that may cause difficulty in pregnancy.
- Difficulty In Embryo Transfer :– It is one of the most common reason for failed IVF procedure. Issues at embryo transfer or blood seen at catheter tips causes high risk of failure.
- Autoimmune Diseases :– If the couple face some autoimmune diseases, there may be risk of recurrent IVF failures. Usually, screening of the couple with repeated pregnancy loss is done to rule out the chance of autoimmune disease.
- The firstly and most importantly you need to get done a thorough examination involving ultrasound and blood tests and then screening for determination of the ovarian reserve and semen analysis.
- After that, you need to go for a laparoscopic hysteroscopy test to look for any physical obstacles in conception.
- Your IVF specialist will freshen the poor-quality endometrium; also, you have to send a sample to rule out the chance of tuberculosis.
- Hydrosalpinges should be clipped during this time to avoid the embryo-toxic fluid from causing IVF failures.
- After following these steps, your IVF specialist will help you and start the right ovarian stimulation.
- Your IVF specialist will make sure that your endometrium is fit for implantation in quality and thickness.
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